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STEMI Equivalent Treatment

Question# 991

In the cases of say a patient presenting with a STEMI equivalent such as De Winters Sign, or presenting with something like a Modified Sgarbossa positive STEMI, would it be acceptable for either a PCP or ACP to administer medications under the Cardiac Ischemia directive as though that patient did have a typical STEMI, and document the clinical reasoning? As in limiting nitro doses to 3 sprays or withholding nitro in cases of suspected RV involvement due to Sgarbossas. Or would this be something to patch to a BHP and have that discussion before making that decision?

Answer:


Yes, administering aspirin and nitroglycerin for STEMI equivalents such as de Winter's sign or a positive Modified Sgarbossa pattern is not only acceptable but guideline-supported, provided the clinical reasoning is documented and standard contraindications are respected. The key principle across current guidelines is that these ECG patterns represent acute coronary artery occlusion and should be managed identically to a classic STEMI.

Cardiac ischemia can present with a whole constellation of symptoms ranging from nausea and “feeling unwell” to your classic retrosternal chest pressure. It is recommended to administer ASA for any patient you suspect of having ischemic chest pain per the medical directive. Unless the patient has a contraindication to ASA, it should be administered to all patients we suspect of having an ischemic event. ASA has a huge mortality benefit, with an exceptional number needed to treat, a wide therapeutic window, and a low risk profile.

The 2022 ACC Expert Consensus Decision Pathway explicitly classifies both de Winter's sign and positive Modified Sgarbossa criteria as STEMI equivalents. De Winter's sign (which MUST have the ST depression followed by the peaked T waves tall, symmetric T waves with upsloping ST depression >1 mm in precordial leads) indicates proximal LAD occlusion and "warrants immediate angiography". For patients meeting Sgarbossa or Modified Sgarbossa criteria, "treatment should be similar to those with STEMI". The 2025 ACC/AHA/ACEP/NAEMSP/SCAI ACS Guideline reinforces that when "ST-segment elevation or an equivalent finding is present on the initial ECG, initial management and triage should follow the prescribed STEMI treatment algorithm".

Thorough documentation of the clinical reasoning — specifically noting the ECG pattern identified, why it was interpreted as a STEMI equivalent, the clinical presentation, and the rationale for treatment — is essential and appropriate.

Having said that, as it stands, STEMI equivalents such as the ones you’ve mentioned, currently don’t meet the criteria for STEMI bypass, and unfortunately, there are no anticipated changes to the STEMI bypass criteria based on these guidelines.

As we’ve shifted towards a more consultative relationship with the base hospital physicians and paramedics, there is always the opportunity to engage in a conversation with a BHP. Lastly, this is an opportunity to advocate strongly for your patient and your concerns to the triage nurse.

For a more nuanced discussion regarding treating cardiac ischemia vs pain, please read the following MedicASKs answers:

https://www.rppeo.ca/paramedic-practice/medicask-about/medicask-answers-list/250-medical-directives/255-cardiac-ischemia/1986-cardiac-ischemia-vs-chest-pain

https://www.rppeo.ca/paramedic-practice/medicask-about/medicask-answers-list/250-medical-directives/255-cardiac-ischemia/1944-cardiac-ischemia-treatment

Published

25 June 2026

ALSPCS Version

5.4

Views

8

Please reference the MOST RECENT ALS PCS for updates and changes to these directives.