Shock Definition and Dopamine
Question# 852
Answer:
Shock is characterized by a condition of cellular and tissue hypoxia, which occurs due to reduced oxygen delivery, increased oxygen consumption, insufficient oxygen utilization, or a combination of these factors.
As you pointed out, shock can be classified in various ways, each with distinct presentations and treatment approaches.
In general, the terms "mechanical" and "obstructive" describe similar underlying issues: extracardiac factors that hinder blood flow, that is a scenario characterized by an obstruction to blood flow that causes significant circulatory compromise and inadequate tissue perfusion. These terms are often used interchangeably.
Examples of mechanical or obstructive shock include tension pneumothorax, cardiac tamponade, pulmonary embolism (PE), constrictive pericarditis, aortic stenosis, tumors (for example, atrial tumor), and dissecting aortic aneurysm.
A useful mnemonic to help identify the cause of shock is:
- S: septic/spinal
- H: hypovolemic
- O: obstructive/mechanical
- C: cardiogenic
- K: anaphylactic (“K”)
Dopamine is used as a vasoconstrictor and as an inotrope. However, tachycardia and vasoconstriction are known effects of dopamine. Together, they can raise cardiac oxygen demand as well as reduce oxygen delivery and that may worsen the patient outcome in cases of obstructive shock. Therefore, dopamine use is contraindicated in patients with obstructive shock.
References
- Definition, classification, etiology, and pathophysiology of shock in adults – UpToDate (https://www.uptodate.com/contents/definition-classification-etiology-and-pathophysiology-of-shock-in-adults?search=mechanicl%20shock&source=search_result&selectedTitle=3%7E150&usage_type=default&display_rank=2)
- -Standl T, Annecke T, Cascorbi I, Heller AR, Sabashnikov A, Teske W. The Nomenclature, Definition and Distinction of Types of Shock. (https://pmc.ncbi.nlm.nih.gov/articles/PMC6323133/)
- Herget-Rosenthal S, Saner F, Chawla LS. Approach to hemodynamic shock and vasopressors (https://pmc.ncbi.nlm.nih.gov/articles/PMC6631076/)
- Ontario Base Hospital Group. 2005. Paramedic Resource Manual: Shock. https://www.lakeridgehealth.on.ca/en/ourservices/resources/0004_-_SHOCK_-_complete.pdf